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Medicine, Medicinal Chemistry, Pharmacology +17

Tyrosine Kinase Inhibitors. 17. Irreversible Inhibitors of the Epidermal Growth Factor Receptor:  4-(Phenylamino)quinazoline- and 4-(Phenylamino)pyrido[3,2-<i>d</i>]pyrimidine-6-acrylamides Bearing Additional Solubilizing Functions

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Medicine, Medicinal Chemistry, Pharmacology +13

Tyrosine Kinase Inhibitors. 15. 4-(Phenylamino)quinazoline and 4-(Phenylamino)pyrido[<i>d</i>]pyrimidine Acrylamides as Irreversible Inhibitors of the ATP Binding Site of the Epidermal Growth Factor Receptor

Jeff B. Smaill, Brian D. Palmer, Gordon W. Rewcastle et al. · Journal of Medicinal Chemistry · 1999 · 179 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Tyrosine Kinase Inhibitors. 9. Synthesis and Evaluation of Fused Tricyclic Quinazoline Analogues as ATP Site Inhibitors of the Tyrosine Kinase Activity of the Epidermal Growth Factor Receptor

Gordon W. Rewcastle, Brian D. Palmer, Alexander J. Bridges et al. · Journal of Medicinal Chemistry · 1996 · 149 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Structure−Activity Relationships for a Novel Series of Pyrido[2,3-<i>d</i>]pyrimidine Tyrosine Kinase Inhibitors

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Pharmacy, Medicinal Chemistry, Pharmacology +17