Jiou Wang

The C9orf72 repeat expansion disrupts nucleocytoplasmic transport

Ke Zhang, Christopher J. Donnelly, Aaron R. Haeusler et al. · Nature · 2015 · 1K citations

Life Sciences, Genetics, Molecular Biology +5

C9orf72 nucleotide repeat structures initiate molecular cascades of disease

Aaron R. Haeusler, Christopher J. Donnelly, Goran Periz et al. · Nature · 2014 · 988 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +7

RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention

Christopher J. Donnelly, Ping‐Wu Zhang, Jacqueline T. Pham et al. · Neuron · 2013 · 882 citations

Life Sciences, Molecular Biology, Neuroscience +16

Fibrillar Inclusions and Motor Neuron Degeneration in Transgenic Mice Expressing Superoxide Dismutase 1 with a Disrupted Copper-Binding Site

Jiou Wang, Guilian Xu, Victoria Gonzales et al. · Neurobiology of Disease · 2002 · 236 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

An ALS-Linked Mutant SOD1 Produces a Locomotor Defect Associated with Aggregation and Synaptic Dysfunction When Expressed in Neurons of Caenorhabditis elegans

Jiou Wang, George W. Farr, David H. Hall et al. · PLoS Genetics · 2009 · 203 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17