Regina Miller

Discovery and Preclinical Evaluation of BMS-955829, a Potent Positive Allosteric Modulator of mGluR5

Fukang Yang, Lawrence B. Snyder, Anand Balakrishnan et al. · ACS Medicinal Chemistry Letters · 2016 · 28 citations · Full text

Drug Target, Psychotropic Medication, Mglur5 Subtype +19

Oxazolidinone-based allosteric modulators of mGluR5: Defining molecular switches to create a pharmacological tool box

Hong Huang, Andrew P. Degnan, Anand Balakrishnan et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 28 citations · Full text

Oxazolidinone-based Allosteric Modulators, Molecular Pharmacology, Biochemistry +9

Development of 1<i>H</i>-Pyrazolo[3,4-<i>b</i>]pyridines as Metabotropic Glutamate Receptor 5 Positive Allosteric Modulators

Matthew D. Hill, Haiquan Fang, Jeffrey M. Brown et al. · ACS Medicinal Chemistry Letters · 2016 · 22 citations · Full text

Effects of BMS-902483, an α7 nicotinic acetylcholine receptor partial agonist, on cognition and sensory gating in relation to receptor occupancy in rodents

Rick L. Pieschl, Regina Miller, Kelli Jones et al. · European Journal of Pharmacology · 2017 · 21 citations

Cognitive Science, Sensory Neuroscience, Neurophysiology +14

Design and Synthesis of a New Series of 4-Heteroarylamino-1′-azaspiro[oxazole-5,3′-bicyclo[2.2.2]octanes as α7 Nicotinic Receptor Agonists. 1. Development of Pharmacophore and Early Structure–Activity Relationship

James A. Cook, F. Christopher Zusi, Ivar M. McDonald et al. · Journal of Medicinal Chemistry · 2016 · 18 citations · Full text