Andrew P. Degnan

Total Synthesis of (+)-13-Deoxytedanolide

Amos B. Smith, Christopher M. Adams, Stephanie A. Barbosa et al. · Journal of the American Chemical Society · 2002 · 114 citations

Enantioselective Synthesis, Bioorganic Chemistry, Biochemistry +11

Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer’s Mouse Phenotypes

Laura T. Haas, Santiago V. Salazar, Levi M. Smith et al. · Cell Reports · 2017 · 107 citations · Full text

Total Syntheses of (−)-Herbertenediol, (−)-Mastigophorene A, and (−)-Mastigophorene B. Combined Utility of Chiral Bicyclic Lactams and Chiral Aryl Oxazolines

Andrew P. Degnan, A. I. MEYERS · Journal of the American Chemical Society · 1999 · 93 citations

Engineering, Organic Chemistry, Chemistry +18

Enhanced antitumor immunity by a novel small molecule HPK1 inhibitor

Dan You, Stephen Hillerman, Gregory Locke et al. · Journal for ImmunoTherapy of Cancer · 2021 · 75 citations · Full text

Discovery of (<i>R</i>)-4-(8-Fluoro-2-oxo-1,2-dihydroquinazolin-3(4<i>H</i>)-yl)-<i>N</i>-(3-(7-methyl-1<i>H</i>-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide (BMS-694153): A Potent Antagonist of the Human Calcitonin Gene-Related Peptide Receptor for Migraine with Rapid and Efficient Intranasal Exposure

Andrew P. Degnan, Prasad V. Chaturvedula, Charles M. Conway et al. · Journal of Medicinal Chemistry · 2008 · 59 citations · Full text