Gregory Locke

Enhanced antitumor immunity by a novel small molecule HPK1 inhibitor

Dan You, Stephen Hillerman, Gregory Locke et al. · Journal for ImmunoTherapy of Cancer · 2021 · 76 citations · Full text

Medicine, Immunology, Pharmacology +17

Potency, selectivity and prolonged binding of saxagliptin to DPP4: maintenance of DPP4 inhibition by saxagliptin in vitro and ex vivo when compared to a rapidly-dissociating DPP4 inhibitor

Aiying Wang, Charles R. Dorso, Lisa M. Kopcho et al. · BMC Pharmacology · 2012 · 60 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Expression, purification, and characterization of human and rat acetyl cfenzyme A carboxylase (ACC) isozymes

Ching-Hsuen Chu, Luping Chen, John N. Feder et al. · Protein Expression and Purification · 2006 · 54 citations

Life Sciences, Biochemistry, Molecular Biology +7

Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1

Andrew P. Degnan, Godwin Kumi, Christopher W. Allard et al. · ACS Medicinal Chemistry Letters · 2021 · 54 citations · Full text

Medicine, Medicinal Chemistry, Oncology +17

Discovery of Non-Nucleotide Small-Molecule STING Agonists <i>via</i> Chemotype Hybridization

Emily C. Cherney, Liping Zhang, Julian B. Lo et al. · Journal of Medicinal Chemistry · 2022 · 34 citations · Full text

Medicine, Oncology, Pharmacology +16