Lisa M. Kopcho

Mechanism of Gly-Pro-pNA cleavage catalyzed by dipeptidyl peptidase-IV and its inhibition by saxagliptin (BMS-477118)

Young B. Kim, Lisa M. Kopcho, Mark Kirby et al. · Archives of Biochemistry and Biophysics · 2005 · 72 citations

Life Sciences, Biochemistry, Pharmacology +12

Helicobacter pylori-selective Antibacterials Based on Inhibition of Pyrimidine Biosynthesis

Robert A. Copeland, Jovita Marcinkeviciene, Tasir S. Haque et al. · Journal of Biological Chemistry · 2000 · 68 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Potency, selectivity and prolonged binding of saxagliptin to DPP4: maintenance of DPP4 inhibition by saxagliptin in vitro and ex vivo when compared to a rapidly-dissociating DPP4 inhibitor

Aiying Wang, Charles R. Dorso, Lisa M. Kopcho et al. · BMC Pharmacology · 2012 · 60 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Parallel Synthesis of Potent, Pyrazole-Based Inhibitors of <i>Helicobacter </i><i>p</i><i>ylori</i> Dihydroorotate Dehydrogenase

Tasir S. Haque, Seifu Tadesse, Jovita Marcinkeviciene et al. · Journal of Medicinal Chemistry · 2002 · 58 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Selective inhibition of bacterial dihydroorotate dehydrogenases by thiadiazolidinediones

Jovita Marcinkeviciene, Michael J. Rogers, Lisa M. Kopcho et al. · Biochemical Pharmacology · 2000 · 53 citations

Life Sciences, Biochemistry, Pharmacology +8