Kwon Soo Chun

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

Travis K. Warren, Robert Jordan, Michael K. Lo et al. · Nature · 2016 · 1.6K citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-<i>f</i>][triazin-4-amino] Adenine <i>C</i>-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses

Dustin S. Siegel, Hon C. Hui, Edward Doerffler et al. · Journal of Medicinal Chemistry · 2017 · 665 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets

Robert M. Cox, Josef D. Wolf, Carolin M. Lieber et al. · Nature Communications · 2021 · 131 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +14

Comparison of 18F-FDG, 18F-FET and 18F-FLT for differentiation between tumor and inflammation in rats

Tae Sup Lee, Soon Hyuk Ahn, Byung Seok Moon et al. · Nuclear Medicine and Biology · 2009 · 95 citations

Medicine, Nuclear Medicine, Oncology +8

Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosine <i>C</i>-Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV

Richard L. Mackman, Hon C. Hui, Michel Perron et al. · Journal of Medicinal Chemistry · 2021 · 90 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15