Concepedia

Richard L. Mackman

RL

Statistics

Publications

76

Citations

9.3K

H-Index

39

Active since

1993

Affiliations

Gilead Sciences (United States)(Current)

Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry

University of North Carolina at Chapel Hill

University of California, San Francisco

Centers for Disease Control and Prevention

Richard L. Mackman is an author at Gilead Sciences (United States) specializing in medicine, pharmacology, and biochemistry.

ORCID

Top concepts

Publications per year

1993–2024

76

Publications

76

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses

Timothy P. Sheahan, Amy Sims, Rachel L. Graham et al. · Science Translational Medicine · 2017 · 1.6K citations · Full text

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

Travis K. Warren, Robert Jordan, Michael K. Lo et al. · Nature · 2016 · 1.6K citations · Full text

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Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

Maria L. Agostini, Erica L. Andres, Amy Sims et al. · mBio · 2018 · 1.5K citations · Full text

Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-<i>f</i>][triazin-4-amino] Adenine <i>C</i>-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses

Dustin S. Siegel, Hon C. Hui, Edward Doerffler et al. · Journal of Medicinal Chemistry · 2017 · 648 citations · Full text

GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses

Michael K. Lo, Robert Jordan, Aaron Arvey et al. · Scientific Reports · 2017 · 504 citations · Full text

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