Masahiro Nishimoto

Discovery of Tofogliflozin, a Novel <i>C</i>-Arylglucoside with an <i>O</i>-Spiroketal Ring System, as a Highly Selective Sodium Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes

Yoshihito Ohtake, Tsutomu Sato, Takamitsu Kobayashi et al. · Journal of Medicinal Chemistry · 2012 · 168 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Distinct substrate specificities of three glycoside hydrolase family 42  -galactosidases from Bifidobacterium longum subsp. infantis ATCC 15697

Alexander Holm Viborg, Takane Katayama, Maher Abou Hachem et al. · Glycobiology · 2013 · 46 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

Fusion of family VI cellulose binding domains to Bacillus halodurans xylanase increases its catalytic activity and substrate-binding capacity to insoluble xylan

Selanere L. Mangala, Farooqahmed S. Kittur, Masahiro Nishimoto et al. · Journal of Molecular Catalysis B Enzymatic · 2003 · 45 citations

Life Sciences, Biochemistry, Microbiology +17

Discovery of Potent and Orally Available Malonyl-CoA Decarboxylase Inhibitors as Cardioprotective Agents

Jie‐Fei Cheng, Yujin Huang, Richard Penuliar et al. · Journal of Medicinal Chemistry · 2006 · 43 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Discovery of thiochroman derivatives bearing a carboxy-containing side chain as orally active pure antiestrogens

Yoshitake Kanbe, Myung-Hwa Kim, Masahiro Nishimoto et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 30 citations

Pharmacy, Medicinal Chemistry, Pharmacology +6