Collagen Fragmentation Promotes Oxidative Stress and Elevates Matrix Metalloproteinase-1 in Fibroblasts in Aged Human Skin

Gary J. Fisher, Taihao Quan, Trupta Purohit, +6

American Journal Of Pathology

FibrosisAged Human SkinCutaneous BiologyPathologyDermal Structure +8

Inhibition of Type I Procollagen Synthesis by Damaged Collagen in Photoaged Skin and by Collagenase-Degraded Collagen in Vitro

James Varani, Dara Spearman, Patricia Perone, +7

American Journal Of Pathology

Tissue EngineeringFibrosisDamaged CollagenCutaneous BiologyCollagenase-degraded Collagen +8

Reduced Expression of Connective Tissue Growth Factor (CTGF/CCN2) Mediates Collagen Loss in Chronologically Aged Human Skin

Taihao Quan, Yuan Shao, Tianyuan He, +2

Journal of Investigative Dermatology

FibrosisCutaneous BiologyMediates Collagen LossWound HealingDermatology +4

Enhancing Structural Support of the Dermal Microenvironment Activates Fibroblasts, Endothelial Cells, and Keratinocytes in Aged Human Skin In Vivo

Taihao Quan, Frank Wang, Yuan Shao, +5

Journal of Investigative Dermatology

Tissue EngineeringRegenerative MedicineAged Human SkinAgingEndothelial Cells +10

Quercetin inhibits UV irradiation-induced inflammatory cytokine production in primary human keratinocytes by suppressing NF-κB pathway

Fabiana T. M. C. Vicentini, Tianyuan He, Yuan Shao, +4

Journal of Dermatological Science

InflammationCutaneous BiologyImmune RegulationImmunologySkin Pharmacology +6

Ultraviolet Irradiation Increases Matrix Metalloproteinase-8 Protein in Human Skin In Vivo

Gary J. Fisher, Hye-Jung Choi, Zsuzsanna Bata‐Csörgõ, +5

Journal of Investigative Dermatology

Cutaneous BiologyPhotocarcinogenesisWound HealingDermatologyMatrix Biology +6

Cbl Promotes Ubiquitination of the T Cell Receptor ζ through an Adaptor Function of Zap-70

Hong-Ying Wang, Yoav Altman, Deyu Fang, +4

Journal of Biological Chemistry

Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1‐phosphate signalling to regulate tumour metastasis

Suriyan Ponnusamy, Shanmugam Panneer Selvam, Shikhar Mehrotra, +6

EMBO Molecular Medicine

Oxidative Inhibition of Receptor-type Protein-tyrosine Phosphatase κ by Ultraviolet Irradiation Activates Epidermal Growth Factor Receptor in Human Keratinocytes

Yiru Xu, Yuan Shao, John J. Voorhees, +1

Journal of Biological Chemistry

Elevated Cysteine-Rich 61 Mediates Aberrant Collagen Homeostasis in Chronologically Aged and Photoaged Human Skin

Taihao Quan, TianYuan He, Yuan Shao, +4

American Journal Of Pathology

InflammationCysteine-rich 61FibrosisAutoimmune DiseaseCutaneous Biology +9