Collagen Fragmentation Promotes Oxidative Stress and Elevates Matrix Metalloproteinase-1 in Fibroblasts in Aged Human Skin

Gary J. Fisher, Taihao Quan, Trupta Purohit, +6

American Journal Of Pathology

FibrosisAged Human SkinCutaneous BiologyPathologyDermal Structure +8

Solar Ultraviolet Irradiation Reduces Collagen in Photoaged Human Skin by Blocking Transforming Growth Factor-β Type II Receptor/Smad Signaling

Taihao Quan, Tianyuan He, Sewon Kang, +2

American Journal Of Pathology

Skin DevelopmentHuman GrowthCutaneous BiologyPhotocarcinogenesisWound Healing +7

Reduced Expression of Connective Tissue Growth Factor (CTGF/CCN2) Mediates Collagen Loss in Chronologically Aged Human Skin

Taihao Quan, Yuan Shao, Tianyuan He, +2

Journal of Investigative Dermatology

FibrosisCutaneous BiologyMediates Collagen LossWound HealingDermatology +4

Quercetin inhibits UV irradiation-induced inflammatory cytokine production in primary human keratinocytes by suppressing NF-κB pathway

Fabiana T. M. C. Vicentini, Tianyuan He, Yuan Shao, +4

Journal of Dermatological Science

InflammationCutaneous BiologyImmune RegulationImmunologySkin Pharmacology +6

Ultraviolet Irradiation Blocks Cellular Responses to Transforming Growth Factor-β by Down-regulating Its Type-II Receptor and Inducing Smad7

Taihao Quan, Tianyuan He, John J. Voorhees, +1

Journal of Biological Chemistry

Reduction of fibroblast size/mechanical force down‐regulates <scp>TGF</scp> ‐β type <scp>II</scp> receptor: implications for human skin aging

Gary J. Fisher, Yuan Shao, Tianyuan He, +4

Aging Cell

EngineeringBiomedical EngineeringDermatologyEcm ProductionSkin Regeneration +19

Epidermal Growth Factor Receptor-dependent, NF-κB-independent Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway Inhibits Ultraviolet Irradiation-induced Caspases-3, -8, and -9 in Human Keratinocytes

Hui Qin Wang, Taihao Quan, Tianyuan He, +3

Journal of Biological Chemistry

Ultraviolet Irradiation Induces Smad7 via Induction of Transcription Factor AP-1 in Human Skin Fibroblasts

Taihao Quan, Tianyuan He, John J. Voorhees, +1

Journal of Biological Chemistry

DermatologyTranscriptional RegulationFibroblast Growth FactorTranscription Factor Ap-1Human Skin Fibroblasts +14

Ultraviolet Irradiation Induces CYR61/CCN1, a Mediator of Collagen Homeostasis, through Activation of Transcription Factor AP-1 in Human Skin Fibroblasts

Taihao Quan, Zhaoping Qin, Yiru Xu, +4

Journal of Investigative Dermatology

FibrosisCutaneous BiologyPhotocarcinogenesisWound HealingTranscription Factor Ap-1 +9

Oxidative exposure impairs TGF-β pathway via reduction of type II receptor and SMAD3 in human skin fibroblasts

Tianyuan He, Taihao Quan, Yuan Shao, +2

AGE

InflammationType Ii ReceptorCutaneous BiologyTgf-β PathwayImmunology +6