Sean Turner

Novel Transient Receptor Potential Vanilloid 1 Receptor Antagonists for the Treatment of Pain:  Structure−Activity Relationships for Ureas with Quinoline, Isoquinoline, Quinazoline, Phthalazine, Quinoxaline, and Cinnoline Moieties

Arthur Gomtsyan, Erol K. Bayburt, Robert G. Schmidt et al. · Journal of Medicinal Chemistry · 2005 · 163 citations · Full text

Pain Medicine, Immunology, Receptor Antagonists +18

Discovery of A-971432, An Orally Bioavailable Selective Sphingosine-1-Phosphate Receptor 5 (S1P₅) Agonist for the Potential Treatment of Neurodegenerative Disorders

Adrian D. Hobson, Christopher M. Harris, Elizabeth L. van der Kam et al. · Journal of Medicinal Chemistry · 2015 · 47 citations · Full text

Cell Death, Experimental Pharmacology, Synaptic Signaling +17

Synthesis and Structure−Activity Relationships of a Novel Series of 2,3,5,6,7,9-Hexahydrothieno[3,2-<i>b</i>]quinolin-8(4<i>H</i>)-one 1,1-Dioxide K_ATP Channel Openers:  Discovery of (−)-(9<i>S</i>)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9- hexahydrothieno[3,2-<i>b</i>]quinolin-8(4<i>H</i>)-one 1,1-Dioxide (A-278637), a Potent K_ATP Opener That Selectively Inhibits Spontaneous Bladder Contractions

William A. Carroll, Robert J. Altenbach, Hao Bai et al. · Journal of Medicinal Chemistry · 2004 · 44 citations

Spontaneous Bladder Contractions, Bioorganic Chemistry, Compound 14 +18

Enantiospecific Synthesis of Annulated Nicotine Analogues from <scp>d</scp>- and <scp>l</scp>-Glutamic Acid. Pyridotropanes

Sean Turner, Hongbin Zhai, Henry Rapoport · The Journal of Organic Chemistry · 2000 · 40 citations

Bioorganic Chemistry, Heterocyclic, Biochemistry +14

Synthesis and Structure−Activity Relationships of a Novel Series of Tricyclic Dihydropyridine-Based K_ATP Openers That Potently Inhibit Bladder Contractions in Vitro

William A. Carroll, Konstantinos A. Agrios, Robert J. Altenbach et al. · Journal of Medicinal Chemistry · 2004 · 36 citations