Adrian D. Hobson

Tricyclic Covalent Inhibitors Selectively Target Jak3 through an Active Site Thiol

Eric R. Goedken, M.A. Argiriadi, David Banach et al. · Journal of Biological Chemistry · 2015 · 96 citations · Full text

Stereoselective construction of quaternary centers at ambient temperature by the highly stereocontrolled migration of groups containing sp-, sp2-, and sp3-hybridized carbon atoms

Charles M. Marson, Andrew J. Walker, Jane Pickering et al. · The Journal of Organic Chemistry · 1993 · 78 citations

Engineering, Natural Sciences, Applied Physics +15

Discovery of A-971432, An Orally Bioavailable Selective Sphingosine-1-Phosphate Receptor 5 (S1P₅) Agonist for the Potential Treatment of Neurodegenerative Disorders

Adrian D. Hobson, Christopher M. Harris, Elizabeth L. van der Kam et al. · Journal of Medicinal Chemistry · 2015 · 47 citations · Full text

Cell Death, Experimental Pharmacology, Synaptic Signaling +17

Highly diastereoselective 1,3-dipolar cycloaddition reactions of trans-2-methylene-1,3-dithiolane 1,3-dioxide with 3-oxidopyridinium and 3-oxidopyrylium betaines: a route to the tropane skeleton

Varinder K. Aggarwal, Richard S. Grainger, Gary Newton et al. · Organic & Biomolecular Chemistry · 2003 · 44 citations

Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design

Justin Dietrich, Kenton L. Longenecker, Noel S. Wilson et al. · Journal of Medicinal Chemistry · 2020 · 41 citations · Full text