Justin Dietrich

The EED protein–protein interaction inhibitor A-395 inactivates the PRC2 complex

Yupeng He, Sujatha Selvaraju, Michael L. Curtin et al. · Nature Chemical Biology · 2017 · 229 citations · Full text

Protein Function, Signal Transduction, Molecular Regulation +7

The design, synthesis, and evaluation of 8 hybrid DFG-out allosteric kinase inhibitors: A structural analysis of the binding interactions of Gleevec®, Nexavar®, and BIRB-796

Justin Dietrich, Christopher Hulme, Laurence H. Hurley · Bioorganic & Medicinal Chemistry · 2010 · 179 citations · Full text

Drug Target, Engineering, Biochemistry +8

Hydrophobic Pockets of HPMC Enable Extremely Short Reaction Times in Water

Desislava Petkova, Niginia Borlinghaus, Sudripet Sharma et al. · ACS Sustainable Chemistry & Engineering · 2020 · 72 citations · Full text

Engineering, Hpmc Enable, Super-hydrophobic Surface +19

Synthesis and biological activity of 2-aminothiazoles as novel inhibitors of PGE2 production in cells

Breland E. Smith, Hui Hua Chang, Federico Medda et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 49 citations · Full text

Biological Activity, Pge2 Production, Biochemistry +8

Discovery of a Ni2+-dependent guanidine hydrolase in bacteria

Dietmar Funck, Malte Sinn, Jennifer R. Fleming et al. · Nature · 2022 · 48 citations

Biochemistry, Reactive Nitrogen Specie, Environmental Microbiology +3