Reinhard Kofler

The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species

Astrid A. Ruefli, Michael J. Ausserlechner, David Bernhard et al. · Proceedings of the National Academy of Sciences · 2001 · 489 citations · Full text

Histone Deacetylase Inhibitor, Apoptosis, Cell Death +16

Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents.

Didier Decaudin, Stephan Geley, Tamara Hirsch et al. · PubMed · 1997 · 302 citations

Chemoprevention Strategy, Mitochondrial Dysfunction, Apoptosis +17

CLP1 links tRNA metabolism to progressive motor-neuron loss

Toshikatsu Hanada, Stefan Weitzer, Barbara Mair et al. · Nature · 2013 · 262 citations · Full text

Trna Metabolism, Neurotransmission, Molecular Neurobiology +2

A Molecular Function Map of Ewing's Sarcoma

Maximilian Kauer, Jozef Ban, Reinhard Kofler et al. · PLoS ONE · 2009 · 191 citations · Full text

Identification of a B cell differentiation factor(s) spontaneously produced by proliferating T cells in murine lupus strains of the lpr/lpr genotype.

Gérald J. Prud’homme, C L Park, Terry M. Fieser et al. · The Journal of Experimental Medicine · 1983 · 186 citations · Full text

Lymphocyte Development, Immunology, Immunologic Mechanism +18