Guifen Xu

Structure guided design of a series of sphingosine kinase (SphK) inhibitors

Darin J. Gustin, Yihong Li, Matthew L. Brown et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 98 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +9

Discovery of AB680: A Potent and Selective Inhibitor of CD73

Kenneth V. Lawson, Jarosław Kalisiak, Erick A. Lindsey et al. · Journal of Medicinal Chemistry · 2020 · 83 citations · Full text

Identification and Characterization of a Non-retinoid Ligand for Retinol-binding Protein 4 Which Lowers Serum Retinol-binding Protein 4 Levels in Vivo

Alykhan Motani, Zhulun Wang, Marion Conn et al. · Journal of Biological Chemistry · 2009 · 79 citations · Full text

Rbp4 Lowering, Retinal Therapies, Insulin Signaling +16

Sphingosine Kinase Activity Is Not Required for Tumor Cell Viability

Karen Rex, Shawn Jeffries, Matthew L. Brown et al. · PLoS ONE · 2013 · 65 citations · Full text

Chemoprevention Strategy, Apoptosis, Cell Death +18

A Selective Prostaglandin E₂ Receptor Subtype 2 (EP2) Antagonist Increases the Macrophage-Mediated Clearance of Amyloid-Beta Plaques

Brian M. Fox, Hilary P. Beck, Philip M. Roveto et al. · Journal of Medicinal Chemistry · 2015 · 59 citations · Full text

Immunology, Macrophage-mediated Clearance, Neurochemical Biomarkers +19