Comparative Genomics of<i>Helicobacter pylori</i>: Analysis of the Outer Membrane Protein Families

Richard A. Alm, James E. Bina, Beth Andrews, +3

Infection and Immunity

ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii

Thomas F. Durand-Réville, Satenig Guler, Janelle Comita-Prevoir, +23

Nature Microbiology

Bacterial ResistanceAntimicrobial SusceptibilityHealth SciencesAntibioticsMedicine +10

Transformation of Brassica napus L. using Agrobacterium tumefaciens: developmentally regulated expression of a reintroduced napin gene

S. E. Radke, Beth Andrews, Maurice M. Moloney, +3

Theoretical and Applied Genetics

BiologyPlant BiologyPlant Molecular BiologyBiosynthesisEngineering +8

Pyrrolamide DNA Gyrase Inhibitors: Fragment-Based Nuclear Magnetic Resonance Screening To Identify Antibacterial Agents

Ann E. Eakin, Oluyinka Green, Neil J. Hales, +22

Antimicrobial Agents and Chemotherapy

Essential EnzymeLead IdentificationAntimicrobial ChemotherapyChemical BiologyPharmaceutical Chemistry +16

Inhibitors of the acetyltransferase domain of N-acetylglucosamine-1-phosphate-uridylyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU). Part 2: Optimization of physical properties leading to antibacterial aryl sulfonamides

S. Stokes, Robert Albert, Ed T. Buurman, +5

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBiosynthesisEngineeringBiochemistryNatural Sciences +12

Selective Inhibitors of Bacterial t-RNA-(N¹G37) Methyltransferase (TrmD) That Demonstrate Novel Ordering of the Lid Domain

Pamela Hill, Ayome Abibi, Robert Albert, +13

Journal of Medicinal Chemistry

Bioorganic ChemistryEngineeringX-ray Cocrystal StructuresMolecular BiologyLid Domain +18

Inhibition of Neisseria gonorrhoeae Type II Topoisomerases by the Novel Spiropyrimidinetrione AZD0914

Günther Kern, Tiffany Palmer, David E. Ehmann, +11

Journal of Biological Chemistry

<i>In Vivo</i> Validation of Thymidylate Kinase (TMK) with a Rationally Designed, Selective Antibacterial Compound

Thomas A. Keating, Joseph Newman, N.B. Olivier, +18

ACS Chemical Biology

Selective Antibacterial CompoundDrug TargetMolecular BiologyAntimicrobial ChemotherapyResistance Mechanisms +16

In Vitro Validation of Acetyltransferase Activity of GlmU as an Antibacterial Target in Haemophilus influenzae

Ed T. Buurman, Beth Andrews, Ning Gao, +7

Journal of Biological Chemistry

GlycobiologyEscherichia ColiAntimicrobial ChemotherapyDrug ResistanceMedical Microbiology +18

A soluble deletion mutant of the human complement receptor type 1, which lacks the C4b binding site, is a selective inhibitor of the alternative complement pathway

Susanne M. Scesney, Savvas C. Makrides, Michael Gosselin, +4

European Journal of Immunology

Molecular ImmunologyComplement SystemSignal TransductionAutoimmune DiseaseSoluble Deletion Mutant +12