S. Stokes

Inhibitors of the acetyltransferase domain of N-acetylglucosamine-1-phosphate-uridylyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU). Part 2: Optimization of physical properties leading to antibacterial aryl sulfonamides

S. Stokes, Robert Albert, Ed T. Buurman et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 85 citations

Medicinal Chemistry, Biosynthesis, Engineering +14

Novel Bacterial NAD ⁺ -Dependent DNA Ligase Inhibitors with Broad-Spectrum Activity and Antibacterial Efficacy <i>In Vivo</i>

Scott D. Mills, Ann E. Eakin, Ed T. Buurman et al. · Antimicrobial Agents and Chemotherapy · 2010 · 78 citations

Antimicrobial Drug Discovery, Biochemistry, Adenosine Analogs +15

First-in-Human Evaluation of the Safety, Tolerability, and Pharmacokinetics of SPR720, a Novel Oral Bacterial DNA Gyrase (GyrB) Inhibitor for Mycobacterial Infections

Angela K. Talley, Archie Thurston, Grayson Moore et al. · Antimicrobial Agents and Chemotherapy · 2021 · 52 citations · Full text

In Vitro Validation of Acetyltransferase Activity of GlmU as an Antibacterial Target in Haemophilus influenzae

Ed T. Buurman, Beth Andrews, Ning Gao et al. · Journal of Biological Chemistry · 2011 · 41 citations · Full text

Glycobiology, Escherichia Coli, Antimicrobial Chemotherapy +20

Advancement of GyrB Inhibitors for Treatment of Infections Caused by <i>Mycobacterium tuberculosis</i> and Non-tuberculous Mycobacteria

S. Stokes, Rajender Vemula, Michael J. Pucci · ACS Infectious Diseases · 2020 · 34 citations