Satenig Guler

ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii

Thomas F. Durand-Réville, Satenig Guler, Janelle Comita-Prevoir et al. · Nature Microbiology · 2017 · 262 citations

Bacterial Resistance, Antimicrobial Susceptibility, Health Sciences +12

Rational design of a new antibiotic class for drug-resistant infections

Thomas F. Durand-Réville, Alita A. Miller, John P. O’Donnell et al. · Nature · 2021 · 134 citations

Antimicrobial Susceptibility, Antibiotics, Rational Design +8

Antibacterial Inhibitors of Gram-Positive Thymidylate Kinase: Structure–Activity Relationships and Chiral Preference of a New Hydrophobic Binding Region

Sameer Kawatkar, Thomas A. Keating, N.B. Olivier et al. · Journal of Medicinal Chemistry · 2014 · 61 citations

Antibiotic Adjuvant, Molecular Biology, Peptide Science +23

Discovery of Selective and Potent Inhibitors of Gram-Positive Bacterial Thymidylate Kinase (TMK)

Gabriel Martínez-Botella, John Breen, J. Emmett Duffy et al. · Journal of Medicinal Chemistry · 2012 · 52 citations · Full text

Essential Enzyme, Molecular Biology, Antimicrobial Chemotherapy +18

Inhibitors of Tumor Progression Loci-2 (Tpl2) Kinase and Tumor Necrosis Factor α (TNF-α) Production:  Selectivity and in Vivo Antiinflammatory Activity of Novel 8-Substituted-4-anilino-6-aminoquinoline-3-carbonitriles

Neal Green, Yonghan Hu, Kristin Janz et al. · Journal of Medicinal Chemistry · 2007 · 45 citations · Full text

Immunology, Cell Death, Pharmacotherapy +18