Kristin Janz

Synthesis and Biological Evaluation of Quinoline Salicylic Acids As P-Selectin Antagonists

Neelu Kaila, Kristin Janz, Silvano DeBernardo et al. · Journal of Medicinal Chemistry · 2006 · 121 citations · Full text

Immunology, Pharmacotherapy, Experimental Pharmacology +19

2-(4-Chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[<i>H</i>]quinoline-4-carboxylic Acid (PSI-697):  Identification of a Clinical Candidate from the Quinoline Salicylic Acid Series of P-Selectin Antagonists

Neelu Kaila, Kristin Janz, Adrian Huang et al. · Journal of Medicinal Chemistry · 2006 · 82 citations · Full text

Immunology, Clinical Candidate, Pharmacotherapy +21

Inhibition of Tpl2 kinase and TNFα production with quinoline-3-carbonitriles for the treatment of rheumatoid arthritis

Yonghan Hu, Neal Green, Lori K. Gavrin et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 61 citations · Full text

Inflammation, Rheumatology, Tnfα Production +13

Discovery of Isoquinolinone Indole Acetic Acids as Antagonists of Chemoattractant Receptor Homologous Molecule Expressed on Th2 Cells (CRTH2) for the Treatment of Allergic Inflammatory Diseases

Neelu Kaila, Bruce Follows, Louis Leung et al. · Journal of Medicinal Chemistry · 2014 · 54 citations · Full text

Asthma, Inflammatory Lung Disease, Lung Inflammation +17

Inhibition of Tpl2 kinase and TNF-α production with 1,7-naphthyridine-3-carbonitriles: Synthesis and structure–activity relationships

Lori K. Gavrin, Neal Green, Yonghan Hu et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 49 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biosynthesis +10