Concepedia

Jaana Tolvanen

JT

7

Publications

965

Citations

7

H-Index

2010

Active since

Affiliations

University of Helsinki(Current)

Helsinki University Hospital

Oulu University Hospital

University of Oulu

Karolinska Institutet

Jaana Tolvanen is an author at University of Helsinki specializing in molecular diagnostics, uterine fibroids, and obstetrics.

Top concepts

Publications per year

2010–2018

7

Publications

7

<i>MED12</i> , the <i>Mediator Complex Subunit 12</i> Gene, Is Mutated at High Frequency in Uterine Leiomyomas

Netta Mäkinen, Miika Mehine, Jaana Tolvanen et al. · Science · 2011 · 645 citations

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Genetic predisposition to uterine leiomyoma is determined by loci for genitourinary development and genome stability

Niko Välimäki, Heli Kuisma, Annukka Pasanen et al. · eLife · 2018 · 85 citations · Full text

Multiple clinical characteristics separate MED12-mutation-positive and -negative uterine leiomyomas

Hanna-Riikka Heinonen, Annukka Pasanen, Oskari Heikinheimo et al. · Scientific Reports · 2017 · 70 citations · Full text

Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19

Min Ju Park, Hailian Shen, Jason M. Spaeth et al. · Journal of Biological Chemistry · 2018 · 65 citations · Full text

MED12 mutations and FH inactivation are mutually exclusive in uterine leiomyomas

Kati Kämpjärvi, Netta Mäkinen, Miika Mehine et al. · British Journal of Cancer · 2016 · 46 citations · Full text

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