Jaana Tolvanen

<i>MED12</i> , the <i>Mediator Complex Subunit 12</i> Gene, Is Mutated at High Frequency in Uterine Leiomyomas

Netta Mäkinen, Miika Mehine, Jaana Tolvanen et al. · Science · 2011 · 660 citations

Medicine, Molecular Biology, Molecular Genetics +17

Genetic predisposition to uterine leiomyoma is determined by loci for genitourinary development and genome stability

Niko Välimäki, Heli Kuisma, Annukka Pasanen et al. · eLife · 2018 · 90 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Multiple clinical characteristics separate MED12-mutation-positive and -negative uterine leiomyomas

Hanna-Riikka Heinonen, Annukka Pasanen, Oskari Heikinheimo et al. · Scientific Reports · 2017 · 72 citations · Full text

Medicine, Gynecology, Pathology +16

Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19

Min Ju Park, Hailian Shen, Jason M. Spaeth et al. · Journal of Biological Chemistry · 2018 · 66 citations · Full text

Medicine, Oncology, Pathology +16

MED12 mutations and FH inactivation are mutually exclusive in uterine leiomyomas

Kati Kämpjärvi, Netta Mäkinen, Miika Mehine et al. · British Journal of Cancer · 2016 · 48 citations · Full text

Medicine, Oncology, Pathology +17