Jason M. Spaeth

Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation

E. Danielle Dean, Mingyu Li, Nripesh Prasad et al. · Cell Metabolism · 2017 · 211 citations · Full text

Life Sciences, Cell Biology, Endocrinology +10

Uterine Leiomyoma-Linked MED12 Mutations Disrupt Mediator-Associated CDK Activity

Mikko Turunen, Jason M. Spaeth, Salla Keskitalo et al. · Cell Reports · 2014 · 159 citations · Full text

Medicine, Molecular Biology, Oncology +16

HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes

Mark A. Russell, Sambra D. Redick, David M. Blodgett et al. · Diabetes · 2019 · 144 citations · Full text

Life Sciences, Endocrinology, Immunology +17

Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19

Min Ju Park, Hailian Shen, Jason M. Spaeth et al. · Journal of Biological Chemistry · 2018 · 66 citations · Full text

Medicine, Oncology, Pathology +16

MED12 mutations link intellectual disability syndromes with dysregulated GLI3-dependent Sonic Hedgehog signaling

Haiying Zhou, Jason M. Spaeth, Nam Hee Kim et al. · Proceedings of the National Academy of Sciences · 2012 · 65 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17