Nicola Hughes - Concepedia

Author

Nicola Hughes

Pharmaceutical Product Development (United States)

Also Known As

Hughes, Nicola, N C Hughes, N Hughes, N. C. Hughes, N.C. Hughes, Nicola C Hughes, Nicola C. Hughes, Nicola Hughes

Publications

2.3K

Citations

H-Index

106

Concepts

All Affiliations

Pharmaceutical Product Development (United States)Covance (United States)Intertek (United States)Celerion (United States)Health Canada

About

Nicola Hughes is an author at Pharmaceutical Product Development (United States) specializing in medicine, pharmacology, and bioanalysis.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	15	20	1.3K
2	Engineering	9	9	285
3	Biochemistry	9	9	318
4	Natural Sciences	5	5	217
5	Allergy	3	3	293

Nicola Hughes

Publications

2.1K

Citations

H-Index

Page 1

	Year	Citations
Human acetyltransferase polymorphisms Denis M. Grant, Nicola Hughes, Susan A. Janezic, Mutation research. Fundamental and molecular mechanisms of mutagenesis Human Acetyltransferase PolymorphismsGeneticsHuman PolymorphismGenetic MechanismMolecular Genetics	1997	266
Small-molecule factor B inhibitor for the treatment of complement-mediated diseases Anna Schubart, Karen Anderson, Nello Mainolfi, Proceedings of the National Academy of Sciences ImmunologyBiological TherapyDermatologyImmunotherapyInflammation	2019	206
Crystal Structure of NLRP3 NACHT Domain With an Inhibitor Defines Mechanism of Inflammasome Inhibition Carien Dekker, Henri Mattes, Michael Wright, Journal of Molecular Biology Crystal StructureAnti-inflammatorySignal TransductionNlrp3 Nacht DomainInflammasome Inhibition	2021	149
Identification and characterization of variant alleles of human acetyltransferase NAT1 with defective function using p-aminosalicylate as an in-vivo and in-vitro probe Nicola Hughes, Susan A. Janezic, Karina L. McQueen, Pharmacogenetics	1998	133
TLR3 and Rig-Like Receptor on Myeloid Dendritic Cells and Rig-Like Receptor on Human NK Cells Are Both Mandatory for Production of IFN-γ in Response to Double-Stranded RNA Ivan Perrot, Florence Deauvieau, Catherine Massacrier, The Journal of Immunology	2010	98
Structural Determinants of MALT1 Protease Activity Christian Wiesmann, Lukas Leder, Jutta Blank, Journal of Molecular Biology Lymphocyte DevelopmentImmune RegulationProteasomeMolecular BiologyImmunology	2012	94
The 2nd Calibration and Validation Group Workshop on Recent Issues in Good Laboratory Practice Bioanalysis Natasha Savoie, Brian Booth, T Hyman Bradley, Bioanalysis EngineeringMeasurementBioanalytical DataValidation Group WorkshopAnalytical Instrumentation	2009	94
Variants of N-acetyltransferase NAT1 and a case-control study of colorectal adenomas Henry J. Lin, Nicole Probst‐Hensch, Nicola Hughes, Pharmacogenetics	1998	80
Small-molecule factor D inhibitors targeting the alternative complement pathway Jürgen Maibaum, Sha-Mei Liao, Anna Vulpetti, Nature Chemical Biology Complement SystemAutoimmune DiseaseAllergyImmunologyAlternative Complement Pathway	2016	74
Covalent binding of dibenzpyrenes and benzo[<i>a</i>]Pyrene to DNA: evidence for synergistic and inhibitory interactions when applied in combination to mouse skin Nicola Hughes, David H. Phillips Carcinogenesis	1990	66

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