Nicola Hughes

Human acetyltransferase polymorphisms

Denis M. Grant, Nicola Hughes, Susan A. Janezic et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis · 1997 · 266 citations

Human Acetyltransferase Polymorphisms, Genetics, Human Polymorphism +3

Small-molecule factor B inhibitor for the treatment of complement-mediated diseases

Anna Schubart, Karen Anderson, Nello Mainolfi et al. · Proceedings of the National Academy of Sciences · 2019 · 206 citations · Full text

Immunology, Biological Therapy, Dermatology +23

Crystal Structure of NLRP3 NACHT Domain With an Inhibitor Defines Mechanism of Inflammasome Inhibition

Carien Dekker, Henri Mattes, Michael Wright et al. · Journal of Molecular Biology · 2021 · 149 citations

Crystal Structure, Anti-inflammatory, Signal Transduction +9

Identification and characterization of variant alleles of human acetyltransferase NAT1 with defective function using p-aminosalicylate as an in-vivo and in-vitro probe

Nicola Hughes, Susan A. Janezic, Karina L. McQueen et al. · Pharmacogenetics · 1998 · 133 citations

TLR3 and Rig-Like Receptor on Myeloid Dendritic Cells and Rig-Like Receptor on Human NK Cells Are Both Mandatory for Production of IFN-γ in Response to Double-Stranded RNA

Ivan Perrot, Florence Deauvieau, Catherine Massacrier et al. · The Journal of Immunology · 2010 · 98 citations · Full text