Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies

Ivan Perrot, Henri‐Alexandre Michaud, Marc Giraudon-Paoli, +23

Cell Reports

Cancer ImmunosurveillanceMedicineImmune Checkpoint InhibitorsImmunologyTumor Immunity +13

Dendritic Cells Infiltrating Human Non-Small Cell Lung Cancer Are Blocked at Immature Stage

Ivan Perrot, Dominique Blanchard, N. Freymond, +4

The Journal of Immunology

Human XCR1+ Dendritic Cells Derived In Vitro from CD34+ Progenitors Closely Resemble Blood Dendritic Cells, Including Their Adjuvant Responsiveness, Contrary to Monocyte-Derived Dendritic Cells

Sreekumar Balan, Vincent Ollion, Nicholas Colletti, +18

The Journal of Immunology

Blood DcDc ExcelImmunologyPathologyImmunologic Mechanism +16

Human CD4+CD25high Regulatory T Cells Modulate Myeloid but Not Plasmacytoid Dendritic Cells Activation

Roch Houot, Ivan Perrot, Eric Garcia, +2

The Journal of Immunology

InflammationAutoimmune DiseaseAllergyMaturation MarkersTlr Ligands +13

TLR3 and Rig-Like Receptor on Myeloid Dendritic Cells and Rig-Like Receptor on Human NK Cells Are Both Mandatory for Production of IFN-γ in Response to Double-Stranded RNA

Ivan Perrot, Florence Deauvieau, Catherine Massacrier, +14

The Journal of Immunology

Leukemic plasmacytoid dendritic cells share phenotypic and functional features with their normal counterparts

Laurence Chaperot, Ivan Perrot, Marie‐Christine Jacob, +7

European Journal of Immunology

Cell proliferation and survival induced by Toll-like receptors is antagonized by type I IFNs

Uzma Hasan, Christophe Caux, Ivan Perrot, +5

Proceedings of the National Academy of Sciences

Innate Immune SystemImmunologyCell DeathImmunologic MechanismCell Proliferation +15

Antitumor immunity induced by antibody-based natural killer cell engager therapeutics armed with not-alpha IL-2 variant

Olivier Demaria, Laurent Gauthier, Marie Vétizou, +46

Cell Reports Medicine

Human natural killer cells promote cross‐presentation of tumor cell‐derived antigens by dendritic cells

Florence Deauvieau, Vincent Ollion, Anne‐Claire Doffin, +13

International Journal of Cancer

Adaptive Immune SystemImmunologyImmune RegulationNk CellsImmunologic Mechanism +16

A tetraspecific engager armed with a non-alpha IL-2 variant harnesses natural killer cells against B cell non-Hodgkin lymphoma

Olivier Demaria, Guillaume Habif, Marie Vétizou, +31

Science Immunology