Graeme Thomson - Concepedia

Author

Graeme Thomson

Also Known As

G. J. Thomson, G. Thomson, G.J Thomson, G.J. Thomson, GRAEME J. THOMSON, GRAEME THOMSON, Graeme J. THOMSON, Graeme J. Thomson, Graeme Thomson, Thomson, Graeme

Publications

728

Citations

H-Index

Concepts

All Affiliations

University of Manchester Cancer Research UK Manchester Institute University of Leeds Cancer Research UK Birkbeck, University of London

About

Graeme Thomson is an author at University of Manchester specializing in natural sciences, medicine, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	9	9	384
2	Medicine	8	8	317
3	Biochemistry	8	8	370
4	Engineering	1	1	17
5	Biology	1	1	14

Graeme Thomson

Publications

706

Citations

H-Index

Page 1

	Year	Citations
Conserved residues in the mechanism of the E. coli class II FBP-aldolase 1 1Edited by J. Karn Andrew Plater, Shaza M. Zgiby, Graeme Thomson, Journal of Molecular Biology Cellular EnzymologyConserved ResiduesBiochemistryNatural SciencesJ. Karn	1999	78
Exploring substrate binding and discrimination in fructose1,6‐bisphosphate and tagatose 1,6‐bisphosphate aldolases Shaza M. Zgiby, Graeme Thomson, Seema Qamar, European Journal of Biochemistry	2000	69
The dhnA gene of Escherichia coli encodes a Class I fructose bisphosphate aldolase Graeme Thomson, Geoffrey J. Howlett, Alison E. Ashcroft, Biochemical Journal	1998	68
Development and evaluation of selective, reversible LSD1 inhibitors derived from fragments James R. Hitchin, Julian Blagg, Rosemary Burke, MedChemComm Pharmaceutical ScienceDrug TargetPeptide SciencePharmacotherapyReversible Lsd1 Inhibitors	2013	63
Novel Steroid Inhibitors of Glucose 6-Phosphate Dehydrogenase Niall M. Hamilton, Martin D. Dawson, Emma Fairweather, Journal of Medicinal Chemistry Molecular PharmacologyMedicinal ChemistryAldehyde DehydrogenaseAlcohol DehydrogenasesBiochemistry	2012	62
Toxoflavins and Deazaflavins as the First Reported Selective Small Molecule Inhibitors of Tyrosyl-DNA Phosphodiesterase II Ali Raoof, Paul Depledge, Niall M. Hamilton, Journal of Medicinal Chemistry	2013	61
A functional role for a flexible loop containing Glu182 in the class II fructose-1,6-bisphosphate aldolase from Escherichia coli 1 1Edited by D. Rees Shaza M. Zgiby, Andrew Plater, Matthew Bates, Journal of Molecular Biology BiosynthesisCellular EnzymologyBiochemistryProtein FoldingD. Rees	2002	51
2-Aminomethylene-5-sulfonylthiazole Inhibitors of Lysyl Oxidase (LOX) and LOXL2 Show Significant Efficacy in Delaying Tumor Growth Deborah A. Smithen, Leo Leung, Mairi Challinor, Journal of Medicinal Chemistry Dual Lox/loxl2 InhibitorsDrug TargetLoxl2 InhibitionTumor BiologyLysyl Oxidase	2019	40
The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity Rebecca Newton, Katherine A. Bowler, Emily M. Burns, European Journal of Medicinal Chemistry Combinatorial ChemistryDrug TargetPharmacotherapyPharmaceutical ChemistryTumor Biology	2016	38
Discovery and Optimization of Allosteric Inhibitors of Mutant Isocitrate Dehydrogenase 1 (R132H IDH1) Displaying Activity in Human Acute Myeloid Leukemia Cells Stuart Jones, Jonathan Ahmet, Kelly Ayton, Journal of Medicinal Chemistry Myeloid DifferentiationAldo-keto ReductaseR132h Idh1Allosteric InhibitorsChemical Biology	2016	37

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