Astrid Ortiz

Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels

Valentin K. Gribkoff, John E. Starrett, Steven I. Dworetzky et al. · Nature Medicine · 2001 · 311 citations

Life Sciences, Neurology, Neuroscience +16

Quinazolinone Derivatives as Orally Available Ghrelin Receptor Antagonists for the Treatment of Diabetes and Obesity

Joachim Rudolph, William P. Esler, Stephen O’Connor et al. · Journal of Medicinal Chemistry · 2007 · 157 citations · Full text

Medicine, Endocrinology, Pharmacology +17

A Novel Long-Acting Selective Neuropeptide Y2 Receptor Polyethylene Glycol-Conjugated Peptide Agonist Reduces Food Intake and Body Weight and Improves Glucose Metabolism in Rodents

Astrid Ortiz, Lucinda F. Milardo, Lynn B. DeCarr et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 69 citations

Medicine, Endocrinology, Pharmacology +17

3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl ]-1,3,4-oxadiazol-2(3<i>H</i>)-one, BMS-191011:  Opener of Large-Conductance Ca²⁺-Activated Potassium (Maxi-K) Channels, Identification, Solubility, and SAR

J. Romine, Scott Martin, Nicholas A. Meanwell et al. · Journal of Medicinal Chemistry · 2007 · 58 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Dual-acting peptide with prolonged glucagon-like peptide-1 receptor agonist and glucagon receptor antagonist activity for the treatment of type 2 diabetes

Thomas H. Claus, Clark Q. Pan, Joanne Buxton et al. · Journal of Endocrinology · 2007 · 46 citations · Full text

Medicine, Endocrinology, Pharmacology +17