Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment

Baisong Mei, Clark Q. Pan, Haiyan Jiang, +13

Blood

Site-Specific Antibody–Drug Conjugation through Glycoengineering

Qun Zhou, James E. Stefano, Charlene Manning, +14

Bioconjugate Chemistry

Site-specific Antibody–drug ConjugationMedicinal ChemistryNative GlycansBioorganic ChemistryBiochemistry +12

Antifibrotic effects of a tissue inhibitor of metalloproteinase-1 antibody on established liver fibrosis in rats

Christopher J. Parsons, Blair U. Bradford, Clark Q. Pan, +16

Hepatology

Liver FibrosisImmunologyPathologyCell DeathCirrhosis +22

Development of a simple and rapid method for producing non‐fucosylated oligomannose containing antibodies with increased effector function

Qun Zhou, Srinivas Shankara, André Roy, +7

Biotechnology and Bioengineering

EngineeringGlycobiologyImmunologyRapid MethodImmunotherapy +17

Variable Structures of Fis-DNA Complexes Determined by Flanking DNA – Protein Contacts

Clark Q. Pan, Steven E. Finkel, Sarah E. Cramton, +3

Journal of Molecular Biology

Nucleic Acid ChemistryDnaBiochemistryVariable StructuresNatural Sciences +6

A Potent and Highly Selective VPAC2 Agonist Enhances Glucose-Induced Insulin Release and Glucose Disposal

Manami Tsutsumi, Thomas H. Claus, Yin Liang, +10

Diabetes

Insulin SignalingGastrointestinal Peptide HormoneMolecular PharmacologyInsulin DeliveryDiabetes Management +16

Structure of the lipoprotein lipase–GPIHBP1 complex that mediates plasma triglyceride hydrolysis

Gabriel Birrane, Anne P. Beigneux, Brian Dwyer, +9

Proceedings of the National Academy of Sciences

Role of viral hemagglutinin glycosylation in anti-influenza activities of recombinant surfactant protein D

Kevan L. Hartshorn, Richard J. Webby, Mitchell R. White, +6

Respiratory Research

Mutational analysis of human DNase I at the DNA binding interface: Implications for DNA recognition, catalysis, and metal ion dependence

Clark Q. Pan, Jana S. Uumer, Andrea Herzka, +1

Protein Science

Design of a Long Acting Peptide Functioning as Both a Glucagon-like Peptide-1 Receptor Agonist and a Glucagon Receptor Antagonist

Clark Q. Pan, Joanne Buxton, Stephanie Yung, +8

Journal of Biological Chemistry