Phillip P. Knowles - Concepedia

Author

Phillip P. Knowles

Birkbeck, University of London

Also Known As

P P Knowles, Phillip Knowles, Phillip P. KNOWLES, Phillip P. Knowles, Phillip P. Knowles

Publications

1.7K

Citations

H-Index

Concepts

All Affiliations

Birkbeck, University of London Cancer Research UK The Honourable Society of Lincoln's Inn Institute of Structural and Molecular Biology University College London

About

Phillip P. Knowles is an author at Birkbeck, University of London specializing in medicine, natural sciences, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	11	11	1.1K
2	Natural Sciences	10	10	954
3	Biochemistry	9	9	926
4	Allergy	2	2	336
5	Engineering	1	1	77

Phillip P. Knowles

Publications

1.6K

Citations

H-Index

Page 1

	Year	Citations
Structure and Chemical Inhibition of the RET Tyrosine Kinase Domain Phillip P. Knowles, Judith Murray‐Rust, Rizaldy P. Scott, Journal of Biological Chemistry Signal TransductionCell RegulationBiochemistrySignaling PathwayRet Kinase Activity	2006	302
New coupling agents for the synthesis of immunotoxins containing a hindered disulfide bond with improved stability in vivo. Philip E. Thorpe, Philip M. Wallace, Phillip P. Knowles, PubMed ImmunotoxicologyDisulfide LinkageImproved StabilityImmunologyHindered Disulfide Bond	1987	204
Effect of chemical deglycosylation of ricin A chain on the in vivo fate and cytotoxic activity of an immunotoxin composed of ricin A chain and anti-Thy 1.1 antibody. David C. Blakey, Graham J. Watson, Phillip P. Knowles, PubMed AllergyImmunotoxicologyMedicineChemical DeglycosylationImmunology	1987	132
A secondary RET mutation in the activation loop conferring resistance to vandetanib Takashi Nakaoku, Takashi Kohno, Mitsugu Araki, Nature Communications	2018	106
Transforming activity of Fbxo7 is mediated specifically through regulation of cyclin D/cdk6 Heike Laman, Juan M. Funes, Hongtao Ye, The EMBO Journal Signal TransductionSignaling PathwayCell RegulationMolecular RegulationNatural Sciences	2005	90
Structure of a Conserved Dimerization Domain within the F-box Protein Fbxo7 and the PI31 Proteasome Inhibitor Rebecca Kirk, Heike Laman, Phillip P. Knowles, Journal of Biological Chemistry Crystal StructurePi31 Proteasome InhibitorF-box Protein Fbxo7Protein AssemblyProteasome	2008	90
Purification of immunotoxins containing ricin A-chain and abrin A-chain using Blue Sepharose CL-6B Phillip P. Knowles, Philip E. Thorpe Analytical Biochemistry EngineeringBiochemistryAbrin A-chainBioanalysisBiotechnology	1987	77
Oncogenic RET Kinase Domain Mutations Perturb the Autophosphorylation Trajectory by Enhancing Substrate Presentation In trans Iván Plaza-Menacho, Karin Barnouin, K.M. Goodman, Molecular Cell	2014	75
Evaluation of four CD22 antibodies as ricin a chain‐containing immunotoxins for the <i>in vivo</i> therapy of human B‐cell leukemias and lymphomas Guo‐Liang Shen, Jialing Li, Maria‐Ana Ghetie, International Journal of Cancer	1988	71
Synthesis, structure–activity relationship and crystallographic studies of 3-substituted indolin-2-one RET inhibitors Luca Mologni, Roberta Rostagno, Stefania Brussolo, Bioorganic & Medicinal Chemistry Structure–activity RelationshipMedicinal ChemistryBiochemistryNatural SciencesMedicine	2010	69

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