David C. Blakey

Challenges and Key Considerations of the Enhanced Permeability and Retention Effect for Nanomedicine Drug Delivery in Oncology

Uma Prabhakar, Hiroshi Maeda, Rakesh K. Jain et al. · Cancer Research · 2013 · 1.4K citations

Nanoparticles, Workshop Discussions, Engineering +18

AZD9150, a next-generation antisense oligonucleotide inhibitor of <i>STAT3</i> with early evidence of clinical activity in lymphoma and lung cancer

David S. Hong, Razelle Kurzrock, Youngsoo Kim et al. · Science Translational Medicine · 2015 · 428 citations · Full text

ZD6126: a novel vascular-targeting agent that causes selective destruction of tumor vasculature.

Peter D. Davis, Graeme J. Dougherty, David C. Blakey et al. · Oxford University Research Archive (ORA) (University of Oxford) · 2002 · 231 citations

Endothelial Cell Morphology, Chemoprevention Strategy, Tumor Biology +17

New coupling agents for the synthesis of immunotoxins containing a hindered disulfide bond with improved stability in vivo.

Philip E. Thorpe, Philip M. Wallace, Phillip P. Knowles et al. · PubMed · 1987 · 204 citations

Immunotoxicology, Disulfide Linkage, Improved Stability +20

Antitumor activity of the novel vascular targeting agent ZD6126 in a panel of tumor models.

David C. Blakey, F. Russell Westwood, Mike Walker et al. · PubMed · 2002 · 176 citations