New coupling agents for the synthesis of immunotoxins containing a hindered disulfide bond with improved stability in vivo.

Philip E. Thorpe, Philip M. Wallace, Phillip P. Knowles, +6

PubMed

ImmunotoxicologyDisulfide LinkageImproved StabilityImmunologyHindered Disulfide Bond +18

Melanoma Differentiation Associated Gene-7 (mda-7): A Novel Anti-Tumor Gene for Cancer Gene Therapy

Abner M. Mhashilkar, Robert D. Schrock, M. Hindi, +16

Molecular Medicine

Effect of chemical deglycosylation of ricin A chain on the in vivo fate and cytotoxic activity of an immunotoxin composed of ricin A chain and anti-Thy 1.1 antibody.

David C. Blakey, Graham J. Watson, Phillip P. Knowles, +1

PubMed

AllergyImmunotoxicologyMedicineChemical DeglycosylationImmunology +11

Bone histomorphometry and vitamin D status after biliopancreatic bypass for obesity

Juliet Compston, S. Vedi, E Gianetta, +3

Gastroenterology

ObesityMetabolic SyndromeBariatric SurgeryBody CompositionBiliopancreatic Bypass +8

Expression of ricin A chain in <i>Escherichia coli</i>

Mary O'Hare, Lynne M. Roberts, Philip E. Thorpe, +3

FEBS Letters

PI3K Blockade by Ad-PTEN Inhibits Invasion and Induces Apoptosis in Radial Growth Phase and Metastatic Melanoma Cells

Alexis Stewart, Abner M. Mhashilkar, Xiaohong Yang, +14

Molecular Medicine

Cytotoxicity of a recombinant ricin‐A‐chain fusion protein containing a proteolytically‐cleavable spacer sequence

Mary O'Hare, Alex N. F. Brown, Khalid Hussain, +6

FEBS Letters

Blocked and non-blocked ricin immunotoxins against the CD4 antigen exhibit higher cytotoxic potency than a ricin A chain immunotoxin potentiated with ricin B chain or with a ricin B chain immunotoxin

Edward J. Wawrzynczak, Graham J. Watson, Alan J. Cumber, +4

Cancer Immunology Immunotherapy

Microbial ToxinAllergyImmunotoxicologyImmunologyNon-blocked Ricin Immunotoxins +6

Vitamin D2 in vertebrate evolution

Alastair Hay, Graham J. Watson

Comparative Biochemistry and Physiology Part B Comparative Biochemistry

BiologyVitamin D2MedicineMorphogenesisMolecular Genetics +3

Humanisation and characterisation of PR1A3, a monoclonal antibody specific for cell-bound carcinoembryonic antigen

Lorna Stewart, Susan Young, Graham J. Watson, +6

Cancer Immunology Immunotherapy

Tumor BiologyMalignant DiseaseCell-bound Carcinoembryonic AntigenMedicinePathology +6