Tumor-infiltrating lymphocyte treatment for anti-PD-1-resistant metastatic lung cancer: a phase 1 trial

Ben Creelan, Chao Wang, Jamie K. Teer, +23

Nature Medicine

Tumor-infiltrating Lymphocyte TreatmentCancer ImmunosurveillanceMedicineImmunologyTumor Immunity +8

HDAC Inhibitors Enhance T-Cell Chemokine Expression and Augment Response to PD-1 Immunotherapy in Lung Adenocarcinoma

Hong Zheng, Weipeng Zhao, Cihui Yan, +13

Clinical Cancer Research

A phase I study of indoximod in patients with advanced malignancies

Hatem Soliman, Susan Minton, Hyo S. Han, +13

Oncotarget

The anti-fibrotic agent pirfenidone synergizes with cisplatin in killing tumor cells and cancer-associated fibroblasts

Melanie Mediavilla-Varela, Kingsley A. Boateng, David Noyes, +1

BMC Cancer

Combination of External Beam Radiotherapy (EBRT) With Intratumoral Injection of Dendritic Cells as Neo-Adjuvant Treatment of High-Risk Soft Tissue Sarcoma Patients

Steven E. Finkelstein, Cristina Iclozan, Marilyn M. Bui, +15

International Journal of Radiation Oncology*Biology*Physics

Radiation TherapyMedicineDendritic CellsNeo-adjuvant TreatmentCancer Treatment +5

Antagonism of adenosine A2A receptor expressed by lung adenocarcinoma tumor cells and cancer associated fibroblasts inhibits their growth

Melanie Mediavilla-Varela, Kimberly A. Luddy, David Noyes, +4

Cancer Biology & Therapy

Chemoprevention StrategyPathologyWarburg EffectCancer BiologyAdenosine A2a Receptor +14

A Novel Antagonist of the Immune Checkpoint Protein Adenosine A2a Receptor Restores Tumor-Infiltrating Lymphocyte Activity in the Context of the Tumor Microenvironment

Melanie Mediavilla-Varela, Julio Castro, Alberto Chiappori, +5

Neoplasia

Tumor-associated Tregs obstruct antitumor immunity by promoting T cell dysfunction and restricting clonal diversity in tumor-infiltrating CD8+ T cells

David Noyes, Arup K. Bag, Saheed Oluwasina Oseni, +5

Journal for ImmunoTherapy of Cancer

Phase II Trial of B7-1 (CD-86) Transduced, Cultured Autologous Tumor Cell Vaccine Plus Subcutaneous Interleukin-2 for Treatment of Stage IV Renal Cell Carcinoma

Mayer Fishman, Terri Hunter, Hatem Soliman, +13

Journal of Immunotherapy

Effects of environmental stressors on lymphocyte proliferation in Florida manatees, Trichechus manatus latirostris

Cathy J. Walsh, Carl A. Luer, David Noyes

Veterinary Immunology and Immunopathology

BiologyEnvironmental StressWildlife EcologyBiotic StressTrichechus Manatus Latirostris +5