Kyriacos Mitrophanous

Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

G. Ralph, Pippa A. Radcliffe, Denise M. Day et al. · Nature Medicine · 2005 · 499 citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Rnai Protects +8

Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial

Stéphane Palfi, Jean Marc Gurruchaga, G. Ralph et al. · The Lancet · 2014 · 432 citations

Gene Therapies, Neurodegenerative Diseases, Dose Escalation +11

Efficient production of germline transgenic chickens using lentiviral vectors

Michael J. McGrew, Adrian Sherman, Fiona M. Ellard et al. · EMBO Reports · 2004 · 379 citations · Full text

Engineering, Genetics, Biotechnology +6

Minimal Requirement for a Lentivirus Vector Based on Human Immunodeficiency Virus Type 1

V. Narry Kim, Kyriacos Mitrophanous, Susan M. Kingsman et al. · Journal of Virology · 1998 · 267 citations · Full text

A Rev-Independent Human Immunodeficiency Virus Type 1 (HIV-1)-Based Vector That Exploits a Codon-Optimized HIV-1 <i>gag-pol</i> Gene

Ekaterini Kotsopoulou, V. Narry Kim, Alan J. Kingsman et al. · Journal of Virology · 2000 · 224 citations