Susan M. Kingsman

A transient three-plasmid expression system for the production of high titer retroviral vectors

Yuko Soneoka, Paula M. Cannon, Emma E. Ramsdale et al. · Nucleic Acids Research · 1995 · 697 citations · Full text

Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

G. Ralph, Pippa A. Radcliffe, Denise M. Day et al. · Nature Medicine · 2005 · 499 citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Rnai Protects +8

Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial

Stéphane Palfi, Jean Marc Gurruchaga, G. Ralph et al. · The Lancet · 2014 · 432 citations

Gene Therapies, Neurodegenerative Diseases, Dose Escalation +11

Conservation of high efficiency promoter sequences in<i>Saccharomyces cerevisiae</i>

Melanie J. Dobson, Mick F. Tuite, Nigel Roberts et al. · Nucleic Acids Research · 1982 · 407 citations · Full text

Transcriptional Regulation, Yeast Genes, Natural Sciences +12

Efficient synthesis of enzymatically active calf chymosin in Saccharomyces cerevisiae

Jane Mellor, Melanie J. Dobson, Nigel Roberts et al. · Gene · 1983 · 333 citations

Biosynthesis, Engineering, Cellular Enzymology +9