Alexander S. McColl

Spontaneous α-N-6-Phosphogluconoylation of a “His Tag” inEscherichia coli:The Cause of Extra Mass of 258 or 178 Da in Fusion Proteins

Kieran F. Geoghegan, H. B. F. Dixon, Philip J. Rosner et al. · Analytical Biochemistry · 1999 · 213 citations

Protein Expression, Biochemistry, Natural Sciences +10

Glycomimetic Ligands for the Human Asialoglycoprotein Receptor

Sreeman Mamidyala, Sanjay Dutta, Boris A. Chrunyk et al. · Journal of the American Chemical Society · 2012 · 102 citations

New Ligands, Medicinal Chemistry, Human Asialoglycoprotein Receptor +14

Discovery and Optimization of a Novel Spiropyrrolidine Inhibitor of β-Secretase (BACE1) through Fragment-Based Drug Design

Ivan Efremov, F.F. Vajdos, Kris A. Borzilleri et al. · Journal of Medicinal Chemistry · 2012 · 63 citations · Full text

Pharmaceutical Science, Drug Target, Novel Spiropyrrolidine Inhibitor +21

Site-directed double fluorescent tagging of human renin and collagenase (MMP-1) substrate peptides using the periodate oxidation of N-terminal serine. An apparently general strategy for provision of energy-transfer substrates for proteases

Kieran F. Geoghegan, Michael J. Emery, William H. Martin et al. · Bioconjugate Chemistry · 1993 · 33 citations

Bioorganic Chemistry, Glycobiology, Lucifer Yellow Fluorescence +19

Isolation and characterization of biologically active murine interleukin-1α derived from expression of a synthetic gene in Escherichia coli

Gaston O. Daumy, Joseph M. Merenda, Alexander S. McColl et al. · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · 1989 · 27 citations

Cytokine, Protein Expression, Immune Regulation +7