Cristian-Mihail Prada

Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo

David Borchelt, Gopal Thinakaran, Christopher B. Eckman et al. · Neuron · 1996 · 1.5K citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1

Karen Duff, Chris Eckman, Cindy Zehr et al. · Nature · 1996 · 1.5K citations

Life Sciences, Neurobiology, Neuroscience +12

A New Pathogenic Mutation in the APP Gene (I716V) Increases the Relative Proportion of A 42(43)

Chris Eckman, Nitin D. Mehta, Richard Crook et al. · Human Molecular Genetics · 1997 · 228 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Amyloid β Protein Starting Pyroglutamate at Position 3 Is a Major Component of the Amyloid Deposits in the Alzheimer's Disease Brain

Yasuo Harigaya, Takaomi C. Saido, Christopher B. Eckman et al. · Biochemical and Biophysical Research Communications · 2000 · 199 citations

Life Sciences, Biochemistry, Neuroscience +17