Amorphous silica nanoparticles induce inflammation via activation of NLRP3 inflammasome and HMGB1/TLR4/MYD88/NF-kb signaling pathway in HUVEC cells

Xuting Liu, Bin Lü, Juanli Fu, +3

Journal of Hazardous Materials

InflammationNanomaterialsNlrp3 InflammasomeImmunologyPharmaceutical Nanotechnology +8

Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: Studies on oxidative stress, inflammation and apoptosis

Xiaomin Xia, Chuanyang Su, Juanli Fu, +6

International Immunopharmacology

InflammationBiochemistryMedicineLiver PhysiologyLipid Peroxidation +8

Bazhen Decoction Protects against Acetaminophen Induced Acute Liver Injury by Inhibiting Oxidative Stress, Inflammation and Apoptosis in Mice

Erqun Song, Juanli Fu, Xiaomin Xia, +2

PLoS ONE

Scientific ValidationBazhen DecoctionImmunologyCell DeathPharmacotherapy +19

Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice

Qiong Shi, Xiufang Song, Juanli Fu, +4

International Immunopharmacology

BiochemistryMedicineLiver PhysiologyParaquat-induced Liver InjuryAnti-apoptosis Effects +6

Selenium supplementation shows protective effects against patulin-induced brain damage in mice via increases in GSH-related enzyme activity and expression

Erqun Song, Chuanyang Su, Juanli Fu, +8

Life Sciences

Selenium DeficiencyGsh-related Enzyme ActivityMedicineLipid PeroxidationSelenium Supplementation +6

Neohesperidin Dihydrochalcone versus CCl₄-Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation

Chuanyang Su, Xiaomin Xia, Qiong Shi, +12

Journal of Agricultural and Food Chemistry

Lipid PeroxidationNhdc TreatmentRedox BiologyPolyphenolicsOxidative Stress +17

Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling

Juanli Fu, Qiong Shi, Xiufang Song, +5

Environmental Toxicology and Pharmacology

InflammationInflammatory ResponsesAnti-inflammatoryMedicineImmunology +9

Neohesperidin dihydrochalcone down-regulates MyD88-dependent and -independent signaling by inhibiting endotoxin-induced trafficking of TLR4 to lipid rafts

Xiaomin Xia, Juanli Fu, Xiufang Song, +4

Free Radical Biology and Medicine

InflammationSignal TransductionNeohesperidin DihydrochalconeCell TraffickingImmunology +8

Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: The prevention of curcumin

Demei Xu, Lihua Hu, Chuanyang Su, +9

Toxicology and Applied Pharmacology

InflammationMedicinal ChemistryAnti-inflammatoryMedicineLiver Physiology +10

Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells

Xiufang Song, Lingrui Li, Qiong Shi, +6

Chemical Research in Toxicology

ApoptosisCell DeathToxicological MechanismOxidative StressPersistent Organic Pollutants +15