Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: Studies on oxidative stress, inflammation and apoptosis

Galactosamine-induced sensitization to the lethal effects of endotoxin.

Chris Galanos, Marina A. Freudenberg, Werner Reutter · Proceedings of the National Academy of Sciences · 1979 · 932 citations · Full text

Veterinary Medicine, Biochemistry, Pharmacology +16

In vivo inhibition of nuclear factor-kappa B activation prevents inducible nitric oxide synthase expression and systemic hypotension in a rat model of septic shock

S F Liu, X Ye, Asrar B. Malik · The Journal of Immunology · 1997 · 259 citations

Life Sciences, Immunology, Pharmacology +15

α-Lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway

Weijian Zhang, Wei Hao, Tory M. Hagen et al. · Proceedings of the National Academy of Sciences · 2007 · 256 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Tumor necrosis factor α in the pathogenesis of human and murine fulminant hepatic failure

Konrad L. Streetz, Ludger Leifeld, Danja Grundmann et al. · Gastroenterology · 2000 · 195 citations · Full text

Medicine, Pathobiology, Pathology +14

NLRP3 inflammasome activation in d-galactosamine and lipopolysaccharide-induced acute liver failure: Role of heme oxygenase-1

Seok‐Joo Kim, Sun‐Mee Lee · Free Radical Biology and Medicine · 2013 · 147 citations

Veterinary Medicine, Immunology, Pathobiology +14