Coibamide A, a Potent Antiproliferative Cyclic Depsipeptide from the Panamanian Marine Cyanobacterium <i>Leptolyngbya</i> sp.

Rebecca A. Medina, Douglas E. Goeger, Patrice Hills, +6

Journal of the American Chemical Society

CyanobacteriaChemical BiologyDrug ResistanceMedicinal ChemistryAntimicrobial Drug Discovery +14

β-Keto sulfones as inhibitors of 11β-hydroxysteroid dehydrogenase type I and the mechanism of action

Jason Xiang, Manus Ipek, Vipin Suri, +7

Bioorganic & Medicinal Chemistry

Molecular PharmacologyMedicinal ChemistryAldehyde DehydrogenaseBiochemistry11β-Hydroxysteroid Dehydrogenase Type +7

Automation of a Fourier transform ion cyclotron resonance mass spectrometer for acquisition, analysis, and e-mailing of high-resolution exact-mass electrospray ionization mass spectral data

Nelson Huang, Marshall M. Siegel, Gary Kruppa, +1

Journal of the American Society for Mass Spectrometry

EngineeringBiological Mass SpectrometrySpectrochemical AnalysisAnalytical InstrumentationData Science +19

A fluorescence-based assay for fatty acid amide hydrolase compatible with high-throughput screening

Manjunath Ramarao, Elizabeth Murphy, Marina W. H. Shen, +6

Analytical Biochemistry

Lipid AnalysisBiochemistryBioanalysisAnalytical BiotechnologyMedicine +4

Mechanism of Inhibition of the Class A β-Lactamases PC1 and TEM-1 by Tazobactam

Youjun Yang, Katarzyna Janota, Keiko Tabei, +5

Journal of Biological Chemistry

A fluorescent assay suitable for inhibitor screening and vanin tissue quantification

Benfang Helen Ruan, Derek C. Cole, Paul W. Wu, +11

Analytical Biochemistry

Preclinical Drug EvaluationBiochemistryMedicineVanin Tissue QuantificationBioanalysis +9

Mechanism of inhibition of the class A beta -lactamases PC1 and TEM-1 by tazobactam. Observation of reaction products by electrospray ionization mass spectrometry.

Youjun Yang, Katarzyna Janota, Keiko Tabei, +5

PubMed

Automated sub-ppm mass accuracy on an ESI-TOF for use with drug discovery compound libraries

Justin G. Stroh, Christopher Petucci, Scott J. Brecker, +2

Journal of the American Society for Mass Spectrometry

Time-of-flight Mass SpectrometryEngineeringHit IdentificationSpectrochemical AnalysisMedicinal Chemistry +21

Aminopyrazole Carboxamide Bruton’s Tyrosine Kinase Inhibitors. Irreversible to Reversible Covalent Reactive Group Tuning

Mark E. Schnute, Stephen Benoit, Ingrid P. Buchler, +28

ACS Medicinal Chemistry Letters

Pharmaceutical ScienceTyrosine KinasePharmacotherapyAminopyrazole Carboxamide ScaffoldExcellent Kinome Selectivity +14

On-line acquisition, analysis, and e-mailing of high-resolution exact-mass electron impact/chemical ionization mass spectrometry data acquired using an automated direct probe

Nelson Huang, Marshall M. Siegel, Helmut Muenster, +1

Journal of the American Society for Mass Spectrometry

On-line AcquisitionClinical Mass SpectrometryBiological Mass SpectrometryChemistrySpectrochemical Analysis +21