Issam Ben Sahra

The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level

Issam Ben Sahra, Kathiane Laurent, Agnès Loubat et al. · Oncogene · 2008 · 847 citations · Full text

Cyclin D1 Level, Antidiabetic Drug Metformin, Antitumoral Effect +8

Targeting Cancer Cell Metabolism: The Combination of Metformin and 2-Deoxyglucose Induces p53-Dependent Apoptosis in Prostate Cancer Cells

Issam Ben Sahra, Kathiane Laurent, Sandy Giuliano et al. · Cancer Research · 2010 · 522 citations

Chemoprevention Strategy, Apoptosis, Cancer Cell Metabolism +16

The combination of metformin and 2 deoxyglucose inhibits autophagy and induces AMPK-dependent apoptosis in prostate cancer cells

Issam Ben Sahra, Jean‐François Tanti, Frédéric Bost · Autophagy · 2010 · 114 citations · Full text

Mitophagy, Apoptosis, Cancer Cell Metabolism +18

Acadesine Kills Chronic Myelogenous Leukemia (CML) Cells through PKC-Dependent Induction of Autophagic Cell Death

Guillaume Robert, Issam Ben Sahra, Alexandre Puissant et al. · PLoS ONE · 2009 · 80 citations · Full text

Imatinib triggers mesenchymal-like conversion of CML cells associated with increased aggressiveness

Alexandre Puissant, Maeva Dufies, Nina Fenouille et al. · Journal of Molecular Cell Biology · 2012 · 37 citations · Full text