Kathiane Laurent

The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level

Issam Ben Sahra, Kathiane Laurent, Agnès Loubat et al. · Oncogene · 2008 · 847 citations · Full text

Cyclin D1 Level, Antidiabetic Drug Metformin, Antitumoral Effect +8

Metformin, Independent of AMPK, Induces mTOR Inhibition and Cell-Cycle Arrest through REDD1

Isaam Ben Sahra, Claire Regazzetti, Guillaume Robert et al. · Cancer Research · 2011 · 611 citations

Targeting Cancer Cell Metabolism: The Combination of Metformin and 2-Deoxyglucose Induces p53-Dependent Apoptosis in Prostate Cancer Cells

Issam Ben Sahra, Kathiane Laurent, Sandy Giuliano et al. · Cancer Research · 2010 · 522 citations

Chemoprevention Strategy, Apoptosis, Cancer Cell Metabolism +16

Inhibition of p38MAPK Increases Adipogenesis From Embryonic to Adult Stages

Myriam Aouadi, Kathiane Laurent, Matthieu Prot et al. · Diabetes · 2006 · 199 citations · Full text

Sestrin2 integrates Akt and mTOR signaling to protect cells against energetic stress-induced death

Issam Ben‐Sahra, Béatrice Dirat, Kathiane Laurent et al. · Cell Death and Differentiation · 2012 · 150 citations · Full text

Inflammation, Reductive Stress, Signal Transduction +11