Local Proliferation of Macrophages Contributes to Obesity-Associated Adipose Tissue Inflammation

Shinya Amano, Jessica Cohen, Pranitha Vangala, +6

Cell Metabolism

ObesityMetabolic SyndromeInflammationLocal ProliferationAdipose Tissue +8

Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation

Myriam Aouadi, Gregory J. Tesz, Sarah M. Nicoloro, +5

Nature

InflammationCytokineImmunologyChronic InflammationMacrophage Map4k4 +3

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

Tony Jourdan, Grzegorz Godlewski, Adeline Bertola, +10

Nature Medicine

InflammationAnti-inflammatoryAutoimmune DiseaseDiabetesAutophagy +12

The Extracellular Signal–Regulated Kinase Isoform ERK1 Is Specifically Required for In Vitro and In Vivo Adipogenesis

Frédéric Bost, Myriam Aouadi, Leslie Caron, +9

Diabetes

Fat-specific Protein 27, a Novel Lipid Droplet Protein That Enhances Triglyceride Storage

Vishwajeet Puri, Silvana Konda, Srijana Ranjit, +5

Journal of Biological Chemistry

EngineeringInflammationMetabolic SyndromeLipid ChemistryLipid Droplet Size +15

Similarity of mouse perivascular and brown adipose tissues and their resistance to diet-induced inflammation

Timothy P. Fitzgibbons, Sophia Kogan, Myriam Aouadi, +3

American Journal of Physiology-Heart and Circulatory Physiology

Metabolic DisorderImmunologyPathologyDiet-induced InflammationOxidative Stress +18

Glutamine Links Obesity to Inflammation in Human White Adipose Tissue

Paul Petrus, Simon Lecoutre, Lucile Dollet, +17

Cell Metabolism

ObesityMetabolic SyndromeInflammationGlutamine Links ObesityBody Composition +10

A subset of Kupffer cells regulates metabolism through the expression of CD36

Camille Blériot, Emelie Barreby, Garett Dunsmore, +41

Immunity

Signal TransductionMolecular PhysiologySignaling PathwayMolecular PathwayCell Regulation +8

Inhibition of p38MAPK Increases Adipogenesis From Embryonic to Adult Stages

Myriam Aouadi, Kathiane Laurent, Matthieu Prot, +3

Diabetes

Coronin 2A mediates actin-dependent de-repression of inflammatory response genes

Wendy Huang, Serena Ghisletti, Kaoru Saijo, +9

Nature

InflammationTranscriptional RegulationSignal TransductionCoronin 2ASignaling Pathway +6