Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition

Anna Segerman, Mia Niklasson, Caroline Haglund, +18

Cell Reports

Clonal VariationNeural Stem CellHigh-grade GliomasCancer BiologyGlioma +19

Mutation patterns in a population-based non-small cell lung cancer cohort and prognostic impact of concomitant mutations in KRAS and TP53 or STK11

Linnéa La Fleur, Elin Falk-Sörqvist, Patrik Smeds, +11

Lung Cancer

Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes

Erika Assarsson, Jason Greenbaum, Magnus Sundström, +12

Proceedings of the National Academy of Sciences

Systems BiologyViral EvolutionMolecular VirologyGeneticsPathogenesis +13

Functional and phenotypic studies of two variants of a human mast cell line with a distinct set of mutations in the <i>c‐kit</i> proto‐oncogene

Magnus Sundström, Harissios Vliagoftis, Peter Karlberg, +4

Immunology

High BRAF Mutation Frequency and Marked Survival Differences in Subgroups According to KRAS/BRAF Mutation Status and Tumor Tissue Availability in a Prospective Population-Based Metastatic Colorectal Cancer Cohort

Halfdan Sørbye, Anca Dragomir, Magnus Sundström, +8

PLoS ONE

Surgical OncologyPathologyOncologyGastrointestinal OncologyTumor Heterogeneity +14

Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity

Markus Rasmussen, Magnus Sundström, Hanna Göransson Kultima, +5

Genome biology

EngineeringCytogeneticsPathologyGenomicsTumor Biology +18

Impact of Thawing on RNA Integrity and Gene Expression Analysis in Fresh Frozen Tissue

Johan Botling, Karolina Edlund, Ulrika Segersten, +5

Diagnostic Molecular Pathology

Rna ProcessingFresh Frozen TissueNatural SciencesGeneticsRna Integrity +13

Data-driven unbiased curation of the <i>TP53</i> tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors

Karolina Edlund, Ola Larsson, Adam Ameur, +7

Proceedings of the National Academy of Sciences

EngineeringPathologyTumor BiologyData-driven Unbiased CurationTumor Heterogeneity +17

KRAS analysis in colorectal carcinoma: Analytical aspects of Pyrosequencing and allele-specific PCR in clinical practice

Magnus Sundström, Karolina Edlund, Monica Lindell, +4

BMC Cancer

Aberrant WNT/β-catenin signaling in parathyroid carcinoma

Jessica Svedlund, Maria Aurén, Magnus Sundström, +4

Molecular Cancer