Rajesh Chopra

Dose intensification with autologous bone-marrow transplantation in relapsed and resistant Hodgkin's disease: results of a BNLI randomised trial

David C. Linch, A. H. Goldstone, Annabel McMillan et al. · The Lancet · 1993 · 1K citations

Transplantation, Marrow Transplantation, Stem Cell Transplantation +9

Outcome of 609 adults after relapse of acute lymphoblastic leukemia (ALL); an MRC UKALL12/ECOG 2993 study

Adele K. Fielding, Susan Richards, Rajesh Chopra et al. · Blood · 2006 · 827 citations · Full text

Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS

Jan Krönke, Emma C. Fink, Paul W. Hollenbach et al. · Nature · 2015 · 816 citations · Full text

Medicine, Cell Death, Pharmacology +2

Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide

Antonia Lopez‐Girona, Derek Mendy, Takumi Ito et al. · Leukemia · 2012 · 783 citations · Full text

Immunomodulatory agents lenalidomide and pomalidomide co‐stimulate <scp>T</scp> cells by inducing degradation of <scp>T</scp> cell repressors <scp>I</scp> karos and <scp>A</scp> iolos via modulation of the <scp>E</scp> 3 ubiquitin ligase complex <scp>CRL</scp> 4 <scp> ^CRBN </scp>

Anita K. Gandhi, Jian Kang, Courtney G. Havens et al. · British Journal of Haematology · 2013 · 611 citations · Full text