Concepedia

Derek Mendy

DM

12

Publications

2.1K

Citations

11

H-Index

2008

Active since

Affiliations

Bristol-Myers Squibb (Switzerland)(Current)

Derek Mendy is an author at Bristol-Myers Squibb (Switzerland) specializing in immunology, cell biology, and immunotherapy.

ORCID

Top concepts

Publications per year

2008–2020

12

Publications

12

Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide

Antonia Lopez‐Girona, Derek Mendy, Takumi Ito et al. · Leukemia · 2012 · 783 citations · Full text

Targeting the p27 E3 ligase SCFSkp2 results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy

Qing Chen, Weilin Xie, Deborah J. Kuhn et al. · Blood · 2008 · 265 citations · Full text

CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells

Christine Surka, Liqing Jin, Nathan Mbong et al. · Blood · 2020 · 208 citations · Full text

Discovery of CRBN E3 Ligase Modulator CC-92480 for the Treatment of Relapsed and Refractory Multiple Myeloma

Joshua D. Hansen, Matthew Correa, Mark A. Nagy et al. · Journal of Medicinal Chemistry · 2020 · 204 citations · Full text

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Lenalidomide downregulates the cell survival factor, interferon regulatory factor‐4, providing a potential mechanistic link for predicting response

Antonia Lopez‐Girona, Daniel Heintel, Ling‐Hua Zhang et al. · British Journal of Haematology · 2011 · 177 citations · Full text

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