J. J. Catino

Antitumor activity of SCH 66336, an orally bioavailable tricyclic inhibitor of farnesyl protein transferase, in human tumor xenograft models and wap-ras transgenic mice.

Ming Liu, Matthew Bryant, Jianping Chen et al. · PubMed · 1998 · 309 citations

Sch 66336, Chemoprevention Strategy, Farnesyl Protein Transferase +15

Production and biological activity of rebeccamycin, a novel antitumor agent.

James Bush, B H Long, J. J. Catino et al. · The Journal of Antibiotics · 1987 · 253 citations · Full text

Interleukin-10 inhibits tumor metastasis through an NK cell-dependent mechanism.

Lie Zheng, David M. Ojcius, F Garaud et al. · The Journal of Experimental Medicine · 1996 · 232 citations · Full text

Immunology, Pathology, Immunologic Mechanism +17

Ras oncoprotein inhibitors: The discovery of potent, ras nucleotide exchange inhibitors and the structural determination of a drug-protein complex

Arthur G. Taveras, Stacy Remiszewski, Ronald J. Doll et al. · Bioorganic & Medicinal Chemistry · 1997 · 121 citations

Molecular Docking, Drug Target, Biochemistry +10

Esperamicins, a class of potent antitumor antibiotics: mechanism of action.

B H Long, Jerzy Golik, Salvatore Forenza et al. · Proceedings of the National Academy of Sciences · 1989 · 119 citations · Full text

Dna Breakage, Pharmacotherapy, Antimicrobial Chemotherapy +18