R. J. A. WALSH

Antitumor imidazotetrazines. 14. Synthesis and antitumor activity of 6- and 8-substituted imidazo[5,1-d]-1,2,3,5-tetrazinones and 8-substituted pyrazolo[5,1-d]-1,2,3,5-tetrazinones

E. Lunt, Christopher G. Newton, Christopher Smith et al. · Journal of Medicinal Chemistry · 1987 · 68 citations

Pharmacy, Medicinal Chemistry, Pharmacology +5

Oxetane synthesis: methyl vinyl sulphides as new traps of excited benzophenone in a stereoselective and regiospecific paterno–Büchi reaction

Trevor Morris, Edward H. Smith, R. J. A. WALSH · Journal of the Chemical Society Chemical Communications · 1987 · 48 citations

Natural Sciences, Chemistry, Organic Chemistry +10

Antitumor imidazotetrazines. 20. Preparation of the 8-acid derivative of mitozolomide and its utility in the preparation of active antitumor agents

Keith R. Horspool, M. F. G. STEVENS, Christopher G. Newton et al. · Journal of Medicinal Chemistry · 1990 · 42 citations

Medicine, Medicinal Chemistry, Pharmacology +5

Selective ET_AAntagonists. 5. Discovery and Structure−Activity Relationships of Phenoxyphenylacetic Acid Derivatives

Peter C. Astles, Thomas J. Brown, Frank Halley et al. · Journal of Medicinal Chemistry · 2000 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Synthesis and biological activity of trans-(.+-.)-N-methyl-2-(3-pyridyl)-2-tetrahydrothiopyrancarbothioamide 1-oxide (RP 49356) and analogs: a new class of potassium channel opener

Thomas J. Brown, Robert F. Chapman, David Cook et al. · Journal of Medicinal Chemistry · 1992 · 38 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15