Effects of hardness on the disintegration time and the dissolution rate of uncoated caffeine tablets

SHIKIFUMI KITAZAWA, IKUO JOHNO, Yoko Ito, +2

Journal of Pharmacy and Pharmacology

Dissolution CharacteristicsEngineeringMineral ProcessingChemical EngineeringDissolution Rate +14

Effect of Xylooligosaccharide Intake on Severe Constipation in Pregnant Women

I Tateyama, Koji Hashii, IKUO JOHNO, +4

Journal of Nutritional Science and Vitaminology

NutritionProbioticMedicineFood DigestionClinical Nutrition +13

Pharmacokinetics of N4-behenoyl-1-beta-D-arabinofuranosylcytosine in patients with acute leukemia.

Takanori Ueda, Toru Nakamura, Seisho Ando, +5

PubMed

Hematological MalignancyBiochemistryMedicineMixed-phenotype Acute LeukemiaBioanalysis +10

Effect of diabetes on disposition and renal handling of cefazolin in rats.

Masayuki Nadai, Hajime Yoshizumi, Takafumi Kuzuya, +3

Drug Metabolism and Disposition

Interpretation of dissolution rate data from <i>in vitro</i> testing of compressed tablets

SHIKIFUMI KITAZAWA, IKUO JOHNO, Tokuzo Minouchi, +1

Journal of Pharmacy and Pharmacology

Pharmaceutical ScienceEngineeringDosage FormBiomedical EngineeringPhysiologically-based Pharmacokinetic Modeling +14

Variations in protein binding of drugs in plasma and serum.

TAEYUKI OHSHIMA, Takaaki Hasegawa, IKUO JOHNO, +1

Clinical Chemistry

Free FractionFree FractionsDrug TargetPharmacological StudyBiochemistry +13

Filtration for Free Drug Level Monitoring

René H. Levy, P. N. Friel, L. M. Linthicum, +6

Therapeutic Drug Monitoring

Comparative Evaluation of Microultrafiltration Devices for Determination of Protein Binding

TAEYUKI OHSHIMA, IKUO JOHNO, SHIKIFUMI KITAZAWA

Therapeutic Drug Monitoring

Direct Determination of Protein Binding of Phenytoin in Serum by High-Performance Liquid Chromatography

TAEYUKI OHSHIMA, IKUO JOHNO, Takaaki Hasegawa, +1

Journal of Pharmaceutical Sciences

BiochemistryDirect DeterminationMedicineBioanalysisAnalytical Chemistry +8

Generality in effects of transmucosal fluid movement and glucose on drug absorption from the rat small intestine.

SHIKIFUMI KITAZAWA, Ito Hajime, IKUO JOHNO, +2

Chemical and Pharmaceutical Bulletin

Sodium ChlorideAnesthesiaGastrointestinal PharmacologyMedicinePhysiology +12