John R. Desjarlais - Concepedia

Author

John R. Desjarlais

Also Known As

Desjarlais, J. R., J Desjarlais, J R Desjarlais, J. Desjarlais, J. R. Desjarlais, J.R. Desjarlais, John Desjarlais, John R Desjarlais, John R. Desjarlais

145

Publications

5.8K

Citations

H-Index

Concepts

All Affiliations

Xencor (United States)Pennsylvania State University University of California, Berkeley Johns Hopkins University Harvard University

About

John R. Desjarlais is an author at Xencor (United States) specializing in medicine, immunotherapy, and immunology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	23	25	3K
2	Natural Sciences	9	9	1.1K
3	Biochemistry	5	5	489
4	Engineering	2	2	173
5	Social Sciences	1	1	61

John R. Desjarlais

Publications

Citations

H-Index

Page 1

	Year	Citations
Enhanced antibody half-life improves in vivo activity Jonathan Zalevsky, Aaron K. Chamberlain, Holly M. Horton, Nature Biotechnology Antibody Half-life ImprovesImmunologyAntibody ScreeningAutoimmunityImmunochemistry	2010	625
De novo design of the hydrophobic cores of proteins John R. Desjarlais, Tracy M. Handel Protein Science	1995	303
Optimization of antibody binding to FcγRIIa enhances macrophage phagocytosis of tumor cells John O. Richards, Sher Karki, Greg A. Lazar, Molecular Cancer Therapeutics	2008	296
Potent <i>In vitro</i> and <i>In vivo</i> Activity of an Fc-Engineered Anti-CD19 Monoclonal Antibody against Lymphoma and Leukemia Holly M. Horton, Matthew J. Bernett, Erik Pong, Cancer Research	2008	267
Inactivation of TNF Signaling by Rationally Designed Dominant-Negative TNF Variants Paul M. Steed, Malú G. Tansey, Jonathan Zalevsky, Science ImmunologyCell DeathPathologyImmunologic MechanismImmunotherapy	2003	257
Use of a zinc-finger consensus sequence framework and specificity rules to design specific DNA binding proteins. John R. Desjarlais, Jeremy M Berg Proceedings of the National Academy of Sciences Protein AssemblyStructural BioinformaticsMolecular BiologySequence MotifProtein Folding	1993	226
Toward rules relating zinc finger protein sequences and DNA binding site preferences. John R. Desjarlais, Jeremy M Berg Proceedings of the National Academy of Sciences Toward RulesCentral Zinc FingerStructural BioinformaticsGeneticsDna Analysis	1992	222
De novo design of the hydrophobic core of ubiquitin Greg A. Lazar, John R. Desjarlais, Tracy M. Handel Protein Science	1997	183
Structural studies of the engrailed homeodomain Neil D. Clarke, Charles R. Kissinger, John R. Desjarlais, Protein Science Structural FeaturesMolecular ReplacementBioorganic ChemistryBiotransformationProtein Assembly	1994	160
Inhibition of B cell receptor-mediated activation of primary human B cells by coengagement of CD19 and FcγRIIb with Fc-engineered antibodies Seung Y. Chu, Igor Voštiar, Sher Karki, Molecular Immunology Adaptive Immune SystemImmune Cell DevelopmentHumoral ResponseImmune RegulationImmunology	2008	148

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