Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis

Walter Hanel, N D Marchenko, Suheng Xu, +3

Cell Death and Differentiation

Tumor BiologyCell RegulationMedicineDifferential GainCell Proliferation +7

Phase II Investigator-Initiated Study of Brentuximab Vedotin in Mycosis Fungoides and Sézary Syndrome With Variable CD30 Expression Level: A Multi-Institution Collaborative Project

Youn H. Kim, Mahkam Tavallaee, Uma Sundram, +13

Journal of Clinical Oncology

Genomic analysis of mycosis fungoides and Sézary syndrome identifies recurrent alterations in TNFR2

Alexander Ungewickell, Aparna Bhaduri, Eon J. Rios, +13

Nature Genetics

Disease MechanismImmunodeficienciesPathogenesisImmunologyGenomic Analysis +8

Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer

Holbrook E. Kohrt, Roch Houot, Kipp Weiskopf, +11

Journal of Clinical Investigation

Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production.

Andrew Plump, Sandra K. Erickson, Wen-Kai Weng, +3

Journal of Clinical Investigation

Apolipoprotein A-iHyperlipidemiaOxidative StressAdrenal GlandSteroidogenic Cells +16

Targeting CD137 enhances the efficacy of cetuximab

Holbrook E. Kohrt, A. Dimitrios Colevas, Roch Houot, +20

Journal of Clinical Investigation

Cancer ImmunosurveillanceNovel TherapyMedicineImmunologyNk Cells +8

Adoptive Immunotherapy with Cytokine-Induced Killer Cells for Patients with Relapsed Hematologic Malignancies after Allogeneic Hematopoietic Cell Transplantation

Ginna G. Laport, Kevin Sheehan, Jeanette Baker, +10

Biology of Blood and Marrow Transplantation

Cell TherapyImmunologyCell Replacement TherapyImmunotherapyAdoptive Immunotherapy +22

The antileukemia activity of a human anti-CD40 antagonist antibody, HCD122, on human chronic lymphocytic leukemia cells

Mohammad Luqman, Sha Klabunde, Karen Lin, +14

Blood

ImmunologyCell DeathAntileukemia ActivityImmunologic MechanismImmunotherapy +16

Minimal Residual Disease Monitoring with High-Throughput Sequencing of T Cell Receptors in Cutaneous T Cell Lymphoma

Wen-Kai Weng, Randall Armstrong, Sally Arai, +3

Science Translational Medicine

Transcriptome sequencing in Sézary syndrome identifies Sézary cell and mycosis fungoides-associated lncRNAs and novel transcripts

Carolyn Lee, Alexander Ungewickell, Aparna Bhaduri, +13

Blood