Shin‐ichi Mihara

Protective Effect of Endothelin Type A Receptor Antagonist on Brain Edema and Injury After Transient Middle Cerebral Artery Occlusion in Rats

Yoshiyuki Matsuo, Shin‐ichi Mihara, Mitsuyoshi Ninomiya et al. · Stroke · 2001 · 127 citations · Full text

Structure−Activity Relationships of a Novel Class of Endothelin-A Receptor Antagonists and Discovery of Potent and Selective Receptor Antagonist, 2-(Benzo[1,3]dioxol-5-yl)-6-isopropyloxy-4-(4-methoxyphenyl)-2<i>H</i>-chromene-3- carboxylic Acid (S-1255). 1. Study on Structure−Activity Relationships and Basic Structure Crucial for ET_A Antagonism

Natsuki Ishizuka, Ken‐ichi Matsumura, Katsunori Sakai et al. · Journal of Medicinal Chemistry · 2002 · 80 citations · Full text

Pharmaceutical Chemistry, Molecular Pharmacology, Medicinal Chemistry +16

A novel non‐peptide endothelin antagonist isolated from bayberry, <i>Myrica cerifera</i>

Masafumi Fujimoto, Shin‐ichi Mihara, Shigeyuki Nakajima et al. · FEBS Letters · 1992 · 74 citations · Full text

Molecular Pharmacology, Biochemistry, Medicine +14

Neuropeptide Y‐induced intracellular Ca²⁺ increases in vascular smooth muscle cells

Shin‐ichi Mihara, Yasushi Shigeri, Masafumi Fujimoto · FEBS Letters · 1989 · 72 citations · Full text

Studies on dihydropyridines. III. Synthesis of 4,7-dihydrothieno(2,3-b)pyridines with vasodilator and antihypertensive activities.

Ikuo Adachi, Teruo Yamamori, Yoshiharu Hiramatsu et al. · Chemical and Pharmaceutical Bulletin · 1988 · 58 citations · Full text

Organic Chemistry, Chemistry, Pharmaceutical Chemistry +16